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Andre J van Wijnen Selected Research

Core Binding Factor Alpha 1 Subunit

4/2013The cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell lines.
2/2013Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice.
3/2010The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells.
12/2009Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells.

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Andre J van Wijnen Research Topics

Disease

58Neoplasms (Cancer)
01/2022 - 07/2003
20Osteoarthritis
06/2022 - 04/2007
20Pain (Aches)
06/2022 - 02/2009
18Inflammation (Inflammations)
01/2021 - 11/2011
17Breast Neoplasms (Breast Cancer)
12/2018 - 02/2005
15Osteosarcoma (Osteogenic Sarcoma)
08/2019 - 09/2003
11Carcinogenesis
01/2019 - 01/2005
11Neoplasm Metastasis (Metastasis)
01/2019 - 06/2006
9Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2018 - 11/2002
8Fibrosis (Cirrhosis)
01/2022 - 06/2009
8Intervertebral Disc Degeneration
08/2020 - 12/2010
8Leukemia
12/2019 - 11/2002
7Genetic Translocation (Chromosomal Translocation)
04/2015 - 05/2005
6Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2021 - 01/2017
6Osteoporosis
01/2019 - 06/2013
6Bone Resorption
01/2019 - 12/2010
6Hyperalgesia
06/2018 - 01/2011
5Infections
01/2020 - 04/2015
4Hypoxia (Hypoxemia)
12/2021 - 01/2016
4Metabolic Bone Diseases (Osteopenia)
01/2021 - 05/2010
4Contracture
11/2020 - 01/2018
4Ataxia Telangiectasia (Louis Bar Syndrome)
12/2019 - 05/2007
4Arthritis (Polyarthritis)
11/2018 - 10/2012
4Osteolysis
11/2016 - 02/2005
4Hypersensitivity (Allergy)
10/2012 - 08/2006
4Prostatic Neoplasms (Prostate Cancer)
03/2010 - 10/2005
3Obesity
06/2021 - 01/2018
3Cicatrix (Scar)
11/2020 - 12/2019
3Bone Diseases (Bone Disease)
11/2016 - 06/2013
3Chronic Pain
10/2011 - 10/2010
3Cleidocranial Dysplasia (Cleidocranial Dysostosis)
05/2010 - 04/2006
2Genomic Instability
10/2021 - 07/2014
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2021 - 11/2016
2Multiple Myeloma
01/2021 - 01/2019
2Renal Artery Obstruction (Renal Artery Stenosis)
01/2021 - 01/2017
2Sarcoma (Soft Tissue Sarcoma)
01/2021 - 12/2014
2Musculoskeletal Diseases (Musculoskeletal Disease)
10/2020 - 01/2019
2Chondrosarcoma
12/2019 - 10/2012
2Glioma (Gliomas)
12/2019 - 05/2015
2Wounds and Injuries (Trauma)
09/2019 - 10/2016
2Rheumatoid Arthritis
09/2019 - 01/2018
2Hypertrophy
03/2019 - 01/2015
2Disease Progression
01/2019 - 01/2018
2Arthralgia (Joint Pain)
06/2018 - 12/2013
2Dupuytren Contracture (Dupuytrens Contracture)
07/2016 - 10/2015
2Triple Negative Breast Neoplasms
06/2016 - 11/2015

Drug/Important Bio-Agent (IBA)

42Proteins (Proteins, Gene)FDA Link
06/2021 - 11/2002
32Transcription Factors (Transcription Factor)IBA
01/2019 - 02/2005
30Biological ProductsIBA
01/2022 - 01/2005
18MicroRNAs (MicroRNA)IBA
01/2021 - 04/2008
12Histones (Histone)IBA
06/2021 - 11/2005
11RNA (Ribonucleic Acid)IBA
01/2022 - 12/2008
11CytokinesIBA
01/2021 - 10/2010
9Messenger RNA (mRNA)IBA
07/2021 - 09/2009
9DNA (Deoxyribonucleic Acid)IBA
06/2021 - 02/2005
8ChromatinIBA
01/2019 - 09/2003
6EnzymesIBA
06/2022 - 10/2007
6CollagenIBA
11/2020 - 01/2015
6Biomarkers (Surrogate Marker)IBA
10/2019 - 01/2014
6Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2013 - 01/2010
5Pharmaceutical PreparationsIBA
01/2019 - 12/2006
4Celecoxib (Celebrex)FDA Link
11/2020 - 01/2011
4Cyclooxygenase 2 (Cyclooxygenase-2)IBA
12/2019 - 01/2011
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2018 - 02/2005
4Histone Deacetylase InhibitorsIBA
12/2017 - 12/2010
4SteroidsIBA
11/2016 - 06/2009
4Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
07/2015 - 04/2007
4Core Binding Factor Alpha 1 SubunitIBA
04/2013 - 12/2009
3Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 02/2016
3Analgesics (Analgesic Drugs)IBA
01/2019 - 05/2018
3OsteopontinIBA
01/2019 - 12/2010
3ChemokinesIBA
01/2018 - 04/2012
3Parathyroid Hormone-Related ProteinIBA
11/2016 - 12/2010
3Nuclear Proteins (Protein, Nuclear)IBA
12/2014 - 05/2007
3Small Interfering RNA (siRNA)IBA
10/2014 - 02/2012
3Interleukin-6 (Interleukin 6)IBA
11/2011 - 01/2009
2Capsules (Microcapsules)IBA
01/2022 - 12/2019
2Plasminogen Activator Inhibitor 1IBA
06/2021 - 01/2020
2Local AnestheticsIBA
01/2021 - 01/2018
2Phosphotransferases (Kinase)IBA
01/2021 - 12/2016
2Mitogen-Activated Protein KinasesIBA
01/2021 - 01/2018
2lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
01/2021 - 01/2017
2Insulin (Novolin)FDA Link
01/2021 - 02/2018
2Ketotifen (Ketotifene)FDA Link
11/2020 - 06/2020
2Follistatin-Related ProteinsIBA
03/2020 - 01/2018
2Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
12/2019 - 05/2015
2MethyltransferasesIBA
12/2019 - 06/2016
2Alkaline PhosphataseIBA
03/2019 - 01/2018
2ProteomeIBA
01/2019 - 01/2017
2MelatoninIBA
04/2018 - 01/2017
2CateninsIBA
11/2017 - 02/2013
2InterleukinsIBA
01/2017 - 10/2016
2Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
01/2017 - 10/2016

Therapy/Procedure

23Therapeutics
06/2022 - 02/2009
6Drug Therapy (Chemotherapy)
01/2018 - 02/2006
5Knee Replacement Arthroplasty (Total Knee Replacement)
12/2021 - 09/2016
4Injections
01/2021 - 10/2016
3Intra-Articular Injections
01/2018 - 10/2010
2Meniscectomy
06/2022 - 05/2018
2Radiotherapy
12/2019 - 01/2017